t regulatory cellの例文


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  1. In addition to its constitutive secretion by CD4 + and CD8 + T cells, the secreted form of FGL2 ( sFGL2 ) can be inducibly secreted by Foxp3 + CD4 + CD25 + T regulatory cells ( T reg s ).
  2. This means that the use of regulatory T cells in therapy may be risky, as the T regulatory cell transferred to the patient may change into T helper 17 ( Th17 ) cells, which are pro-inflammatory rather than regulatory cells.
  3. T regulatory cell adhesion to antigen presenting dendritic cell causes sequestration of Fascin-1, an actin-bundling protein essential for immunological synapse formation, and skews Fascin-1 dependent actin polarization in antigen presenting dendritic cells toward the T reg cell adhesion zone.
  4. A human study of IL-7 in patients with cancer demonstrated that administration of this cytokine can transiently disrupt the homeostasis of both CD8 + and CD4 + T cells with a commensurate decrease in the percentage of CD4 + CD25 + Foxp3 + T regulatory cells.
  5. "Pillai, A ., George, T . I ., Dutt, S ., and Strober, S . Host natural killer T cells induce an interleukin-4-dependent expansion of donor CD4 + CD25 + Foxp3 + T regulatory cells that protects against graft-versus-host disease.


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