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- The cold agglutinin detected is of anti-i specificity.
- This is the case in both cold agglutinin disease and cold paroxysmal hematuria.
- Individuals with cold agglutinin disease present with signs and symptoms of hemolytic anemia.
- It was recognized that the serum of the reported woman agglutinin when described.
- There are also reports of eculizumab being used to treat cold agglutinin disease.