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- Beneath the apical membrane are many vacuoles and dense bodies.
- This protein localizes to tight junctions and to the apical membrane of epithelial cells.
- The proteins cross the apical membrane by endocytosis.
- The O-linked glycosylation is necessary to target the protein to the apical membrane.
- At the apical membranes of the liver and kidney, it enhances excretion of xenobiotics.