rat strainsの例文


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  1. Even between different mouse or rat strains there may be tenfold to thousandfold differences in acute toxicity.
  2. Examples include the BALB / c mouse and Wistar and Sprague Dawley rat strains, laboratory rabbits, guinea-pigs and ferrets.
  3. This is equivalent to a dose of 20 to 30 ?g / kg TCDD, a dose that would be lethal to guinea pigs and some rat strains.
  4. Rat strains are generally not transgenic, or genetically modified, because the gene knockout and embryonic stem cell techniques that work in mice are relatively difficult in rats.
  5. The oral LD50 for guinea pigs is as low as 0.5 to 2 ?g / Kg body weight, whereas the oral LD50 for hamsters can be as high as 1 to 5 mg / Kg body weight, a difference of as much as thousandfold or more, and even among rat strains there may be thousandfold differences.


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