rate-limiting stepの例文
- A rate - limiting step to long - term survival in heart transplant patients is coronary arteriopathy , which is marked intimal proliferation with lumenal narrowing of the small epicardial and intramyocardial coronary artery branches , leading to ischemic changes
- Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin , diphtheria toxin , shiga toxin and pseudomonas exotoxin ( pe ) . a number of these toxins are transported to trans - golgi network ( tgn ) , and in many cases such transport to the tgn is required for the translocation and cytotoxicity . in deed , 5 % of the ricin endocytosed by cells has been shown to reach the tgn
- In order to break down the rate - limited steps in the artemisinin biosynthesis to improve the artemisinin production and realize the industrial production of artemisinin , related key genes in artemisinin biosynthesis must be cloned and the regulatory patterns of key genes should be studied . for this purpose molecular cloning of related key genes in artemisinin biosynthesis was performed in this thesis work
