1. The NCS family were defined by the photoreceptor cell-specific protein, recoverin.
  2. Recoverin, another calcium binding protein, is normally bound to Rhodopsin Kinase when calcium is present.
  3. With this unique pattern of expression it is thought that neurcalcin offers a different physiological role than similar proteins visinin and recoverin.
  4. When the calcium levels fall during phototransduction, the calcium dissociates from recoverin, and rhodopsin kinase is released, when it proceeds to phosphorylate metarhodopsin II, which decreases its affinity for transducin.


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