admeの例文

• The rule describes distribution, metabolism, and excretion ( " ADME " ).
• In 1999 he moved to Lilly to build a predictive ADME / Tox group.
• He was responsible for developing computational models for ADME / Tox and targets of interest.
• During this time he developed an interest in the polypharmacology of ADME / Tox proteins.
• It is challenging to use these compounds as drugs due to their lack of suitable ADME properties.
• Although URSEA and ADME were established, they cannot yet fulfil most of the functions established in their mandate.
• In late 1998 Ekins joined Pfizer and continued his interest in predicting drug-drug interactions and ADME properties.
• 2014 saw the introduction of the new resource ADME SARfari-a tool for predicting and comparing cross-species ADME targets.
• 2014 saw the introduction of the new resource ADME SARfari-a tool for predicting and comparing cross-species ADME targets.
• IdMOC can also be used for routine and high throughput screening of drugs with desirable ADME or ADME-Tox properties . discovery process.
• IdMOC can also be used for routine and high throughput screening of drugs with desirable ADME or ADME-Tox properties . discovery process.
• Martin has particularly focused on identifying properties of molecules relevant to biological activity, including their potency, binding affinity, and ADME properties.
• Application of ADME-Tox tools has increased the success rate of drug development as well as helped in reducing the cost and time factors.
• One of the major innovative products from Scienova is equilibrium dialyzer developed for the high-throughput ADME screenings, especially for Protein Binding Studies.
• The PharmaADME consortium identified 32 core genes containing 184 variants within common pathways that should be included in ADME candidate gene studies of toxicity biomarkers.
• Other authors include the drug s toxicological aspect in what is known as " ADME-Tox " or " ADMET ".
• PBPK models strive to be mechanistic by mathematically transcribing anatomical, physiological, physical, and chemical descriptions of the phenomena involved in the complex ADME processes.
• In the context of pharmacokinetics ( what the body does to a drug ), the distribution coefficient has a strong influence on ADME properties of the drug.
• Other " Phase I " studies aim to investigate how the new drug is absorbed, distributed, metabolised and excreted ( so-called ADME studies ).
• The majority of toxgnostic studies have been candidate gene studies restricted to the known Absorption, Distribution, Metabolism, and Excretion genes ( ADME ) of drug treated patients.