简体版 繁體版 English 한국어
登録 ログイン

androstanediolの例文

例文モバイル版携帯版

  • ? 5-Diol possesses potent estrogenic activity, similarly to DHEA and 3?-androstanediol.
  • Men of Asian ancestry, with the lowest levels of testosterone-activating androstanediol glucuronide, have the lowest levels of prostate cancer.
  • In addition to DHT, dutasteride prevents the 5?-reductase-mediated formation of neurosteroids such as allopregnanolone,, and 3?-androstanediol ( see also neurosteroidogenesis inhibitor ).
  • Etiocholanes include 5?-androstanedione, 5?-dihydrotestosterone, 3?, 5?-androstanediol, 3?, 5?-androstanediol, etiocholanolone, epietiocholanolone, and 3?, 5?-androstanol.
  • Etiocholanes include 5?-androstanedione, 5?-dihydrotestosterone, 3?, 5?-androstanediol, 3?, 5?-androstanediol, etiocholanolone, epietiocholanolone, and 3?, 5?-androstanol.
  • Ligand-gated ion channels such as the GABA A receptor and the NMDA receptor bind and are modulated by neurosteroids such as dehydroepiandrosterone ( DHEA ), allopregnanolone, and 3?-androstanediol.
  • 3?-ADG is used as a marker of target tissue cellular action . 3?-ADG correlates with level of 5?-reductase activity ( testosterone and 3?-androstanediol to dihydrotestosterone ) in the skin.
  • Epiandrosterone is naturally produced by the enzyme 5?-reductase from the adrenal hormone DHEA . Epiandrosterone can also be converted from the natural steroids androstanediol via 17?-hydroxysteroid dehydrogenase or from androstanedione via 3?-hydroxysteroid dehydrogenase.
  • This is in accordance with other 3?-hydroxy steroids, including isopregnanolone, epipregnanolone, 3?-dihydroprogesterone, and 3?-androstanediol, which similarly do not act as such, in contrast to their 3?-hydroxy variants.
  • An orally active synthetic analogue of 3?-androstanediol, 17?-ethynyl-5?-androstane-3?, 17?-diol ( HE-3235, Apoptone ), was formerly under investigation for the treatment of prostate cancer and breast cancer.
  • Several metabolites of testosterone and, including estradiol, 3?-androstanediol, and 3?-androstanediol, are estrogens ( mainly potent [ [ ER? | ] ] agonists in the cases of the latter two ), and 3?-androstanediol is additionally a potent GABA A receptor-potentiating neurosteroid.
  • Several metabolites of testosterone and, including estradiol, 3?-androstanediol, and 3?-androstanediol, are estrogens ( mainly potent [ [ ER? | ] ] agonists in the cases of the latter two ), and 3?-androstanediol is additionally a potent GABA A receptor-potentiating neurosteroid.
  • Several metabolites of testosterone and, including estradiol, 3?-androstanediol, and 3?-androstanediol, are estrogens ( mainly potent [ [ ER? | ] ] agonists in the cases of the latter two ), and 3?-androstanediol is additionally a potent GABA A receptor-potentiating neurosteroid.
  • Other endogenous estrogens, the biosyntheses of which do not involve aromatase, include 27-hydroxycholesterol, dehydroepiandrosterone ( DHEA ), 7-oxo-DHEA, 7?-hydroxy-DHEA, 16?-hydroxy-DHEA, 7?-hydroxyepiandrosterone, 4-androstenedione, 5-androstenediol, 3?-androstanediol, and 3?-androstanediol, and may have important endogenous functions as estrogens.
  • Other endogenous estrogens, the biosyntheses of which do not involve aromatase, include 27-hydroxycholesterol, dehydroepiandrosterone ( DHEA ), 7-oxo-DHEA, 7?-hydroxy-DHEA, 16?-hydroxy-DHEA, 7?-hydroxyepiandrosterone, 4-androstenedione, 5-androstenediol, 3?-androstanediol, and 3?-androstanediol, and may have important endogenous functions as estrogens.
  • Due to the fact that bicalutamide does not lower testosterone levels, the levels of these metabolites would not be expected to be lowered either, unlike with therapies such as analogues . ( Indeed, testosterone,, and estradiol levels are actually raised by bicalutamide treatment, and for this reason, levels of 3?-and 3?-androstanediol might be elevated to some degree similarly . ) These metabolites of testosterone have been found to have-independent positive effects on sexual motivation, and may explain the preservation of sexual interest and function by bicalutamide and other . and may account for the lower incidence of depression with bicalutamide and other relative to other antiandrogen therapies.